Lucky Patcher is an application manager and modification tool developed for Android. Therefore, it is not possible to use it in video games running on Windows. However, some alternative ways are worth mentioning.
First of all, you should keep in mind that Lucky Patcher only works on Android. This tool is not available on any other current operating system, such as iOS, Windows, or macOS. However, there is a partial solution that may satisfy some users: running Android applications on Windows. This is possible by installing an emulator. By doing so, you create a virtual machine that simulates the Android environment, and where games and apps developed for the Google operating system such as Lucky Patcher can be installed. Of course, it is not a definitive or perfect solution, since Lucky Patcher would run in a closed environment and would not be able to interact with the software of our PC, only with the emulator games. Therefore, it is impossible to modify games designed to run on Windows. However, if you still want to play Android games on your PC, you can use BlueStacks, a complete virtual machine frequently used for this purpose, and Lucky Patcher if that was your intention.
On the other hand, there is modification software specifically designed for Windows and its game collection. An example is Cheat Engine, a tool that lets you apply tricks to games as popular and famous as FIFA. Thanks to this application, you can adjust the difficulty of your games in those games that run on Windows.
Although Lucky Patcher does not work in Windows, you can use it in your Android device for many things. Beyond modifying video games, it is capable of extracting APKs from your applications, modifying their permissions, or even removing junk applications that come pre-installed on your device. Note that for many of these functions, you need root access.